Il3 Rat Monoclonal Antibody [Clone ID: 9D19]

CAT#: AM33477PU-N

Il3 rat monoclonal antibody, clone 9D19, Purified

Specifications

Product Data

• Clone Name: 9D19
• Applications: NEUT, WB
• Recommended Dilution: Western Blot: 1/50-1/200.
  Neutralization of IL-3 bioactivity.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant Murine IL-3 protein.
  This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat).
• Specificity: This antibody detects specifically Mouse IL-3 with Western Blot.
• Formulation: State: Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore the antibody with 0.2 ml sterile PBS and the final concentration is 0.5 mg/ml.
• Purification: Affinity Chromatography on Protein A/G
• Database Link:
  Entrez Gene 16187 Mouse
• Background: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.
• Synonyms: IL-3, Multipotential colony-stimulating factor, Hematopoietic growth factor, P-cell-stimulating factor, MCGF