Angiotensin Converting Enzyme 2 (ACE2) (C-term) Mouse Monoclonal Antibody [Clone ID: 11A31]

CAT#: AM33487PU-N

Angiotensin Converting Enzyme 2 (ACE2) (C-term) mouse monoclonal antibody, clone 11A31, Purified

Specifications

Product Data

• Clone Name: 11A31
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human ACE-2 recombinant protein (extracellular domain).
• Specificity: This antibody was selected for its ability to detect ACE-2.
• Formulation: Sterile PBS
  State: Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with 0.2 ml sterile water to the final concentration is 0.5 mg/ml.
• Purification: Affinity Chromatography on Protein G
• Database Link:
  Entrez Gene 59272 Human
• Background: The protein encoded by the gene ACE belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
• Synonyms: Angiotensin-converting enzyme 2