NDE1 Mouse Monoclonal Antibody [Clone ID: AT1F7]

CAT#: AM39076PU-S

Mouse Monoclonal Anti-NDE1 Antibody, Purified

Product Images

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NDE1antibody Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system

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  Western blot analysis: The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NDE1antibody Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT1F7
• Applications: WB
• Recommended Dilution: ELISA, WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human NDE1 (1-335aa) purified from E. coli
• Specificity: The antibody recognizes human NDE1. Other species not tested.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
• Concentration: 1 mg/ml
• Purification: Protein-G affinity chromatography
• Predicted Protein Size: 37.5 kDa
• Gene Name: nudE neurodevelopment protein 1
• Database Link:
  NP_060138
  Entrez Gene 54820 Human
• Background: NDE1 is important to microtubule reorganization, which is required for centrosome duplication and the formation of the mitotic spindle and cell migration. NDE1 is a binding partner of DISC1 along with LIS1 at the centrosome and at synapses in neurons. Mutations in the NDE1 gene result in a reduced cerebral cortex size caused by defects in mitotic progression and chromosomal localization of cortical progenitors. NDE1 is expressed as 2 isoforms produced by alternative splicing of the primary gene transcript.
• Synonyms: HOM-TES-87; LIS4; MHAC; NDE; NUDE; NUDE1