MEMO1 Mouse Monoclonal Antibody [Clone ID: AT1E9]

CAT#: AM50017PU-S

MEMO1 mouse monoclonal antibody, clone AT1E9, Purified

Product Images

Western blot using MEMO1 antibody no. : The cell lysates of Jurkat (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MEMO1 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT1E9
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western blot: 1/3000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human MEMO1 (1-297aa) purified from E. coli
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Protein-G affinity chromatography
• Gene Name: Homo sapiens mediator of cell motility 1 (MEMO1), transcript variant 1
• Database Link:
  Entrez Gene 51072 Human
• Background: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity
• Synonyms: C2orf4, NS5ATP7, CGI-27