alpha Synuclein (SNCA) Mouse Monoclonal Antibody [Clone ID: AT1E10]

CAT#: AM50030PU-N

alpha Synuclein (SNCA) mouse monoclonal antibody, clone AT1E10, Purified

Product Images

The recombinant human synuclein family (alpha-, beta- and gamma-) proteins (100ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human alpha-synuclein antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT1E10
• Applications: ELISA, IF, WB
• Recommended Dilution: ELISA.
  Western blot.
  Immunofluorescence.
  
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human alpha-synuclein (1-140aa) purified from E. coli
• Specificity: This antibody recognizes Human Alpha-Synuclein. Other species not tested.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1
• Database Link:
  Entrez Gene 6622 Human
• Background: Alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.
• Synonyms: NACP, PARK1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Parkinson's disease