STOM Mouse Monoclonal Antibody [Clone ID: AT33F5]
Other products for "STOM"
Specifications
Product Data | |
Clone Name | AT33F5 |
Applications | ELISA, WB |
Recommended Dilution | The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant human STOM (55-288aa) purified from E. coli |
Formulation | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-A affinity chromatography |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens stomatin (STOM), transcript variant 1 |
Database Link | |
Background | STOM(stomatin) is a member of a highly conserved family of integral membrane proteins. This protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of STOM is associated with hereditary stomatocytosis, a form of hemolytic anemia. Although the wide distribution of stomatin and its constitutive expression suggest an important role for this protein in cell biology, perhaps as a house-keeping component, its function remains undetermined. The massive presence of stomatin in membrane-protruding folds and extensions suggests a possible structural role for this protein in the formation of these structures and/or the anchorage to the actin cytoskeleton. |
Synonyms | BND7, EPB72 |
Reference Data | |
Protein Families | Transmembrane |
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