CD11b (ITGAM) Rat Monoclonal Antibody [Clone ID: M1/70]

CAT#: AM50206PU-S

CD11b (ITGAM) rat monoclonal antibody, clone M1/70, Purified


USD 430.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name M1/70
Applications IF, IHC, IP
Recommended Dilution ELISA: Use BSA free Antibody for coating.
Flow Cytometry: 0.5-1 μg/million cells.
Immunofluorescence: 0.5-1 μg/ml.
Functional Studies: Use Antibody without BSA and Azide.
Immunoprecipitation: 0.5-1 μg/500 μg protein lysate.
Immunohistochemistry on Frozen Sections: 0.5-1.0 μg/ml for 30 minutes at RT.
Positive Control: Monocytes & granulocytes, Lymph nodes and tonsils.
Reactivities Chimpanzee, Human, Mouse, Rabbit, Baboon
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen B10 Mouse spleen cells enriched for T lymphocytes.
Specificity CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin åM combines with the Integrin ∫2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin åM/∫2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Cellular Localization: Cell surface.
Formulation 10mM PBS
State: Purified
State: Liquid purified IgG fraction from Bioreactor Concentrate
Stabilizer: 0.05% BSA
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein A/G Chromatography
Storage Store undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Predicted Protein Size 95 kDa & 170 kDa
Gene Name integrin subunit alpha M
Synonyms ITGAM, CR3A, CR-3 alpha chain, Integrin alpha-M, MAC1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.