CD2 Mouse Monoclonal Antibody [Clone ID: UMCD2]

CAT#: AM50214PU-T

CD2 mouse monoclonal antibody, clone UMCD2, Purified


USD 240.00

2 Weeks*

Size
    • 20 ug

Product Images

Specifications

Product Data
Clone Name UMCD2
Applications FC, IF, IHC, IP, WB
Recommended Dilution ELISA: Use BSA free Antibody for coating.
Functional Studies: Use Azide free Antibody. 
Flow Cytometry: 0.5-1 µg/million cells. 
Immunofluorescence: 0.5-1 µg/ml. 
Western Blotting: 0.5-1 µg/ml.
Immunoprecipitation: 0.5-1 µg/500 µg protein lysate. 
Immunohistochemistry on Frozen Sections: 0.5-1 µg/ml for 30 minutes at RT.
Positive Control: 293T or Jurkat cells. Lymph node and tonsil.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human Thymocytes/Sezary T cells.
Specificity Recognizes CD2.
Cellular Localization: Cell surface.
Formulation 10mM PBS
State: Purified
State: Liquid purified IgG fraction from Bioreactor Concentrate
Stabilizer: 0.05% BSA
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein A/G Chromatography
Storage Store undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Predicted Protein Size 50 kDa
Gene Name CD2 molecule
Background CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Synonyms SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.