M6PR Mouse Monoclonal Antibody [Clone ID: AT2B4]

CAT#: AM50329PU-N

M6PR mouse monoclonal antibody, clone AT2B4, Purified

Specifications

Product Data

• Clone Name: AT2B4
• Applications: ELISA, WB
• Recommended Dilution: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human M6PR (27-185aa) purified from E. coli.
• Specificity: This antibody recognizes Human M6PR. Other species not tested.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 1
• Database Link:
  Entrez Gene 4074 Human
• Background: Mannose 6 Phosphate Receptor (Cation dependent) transports phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
• Synonyms: 46 kDa mannose 6-phosphate receptor, MPR46, MPRD, CD Man-6-P receptor, CD-MPR

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Lysosome