IGF1 Mouse Monoclonal Antibody [Clone ID: AT6F8]

CAT#: AM50335PU-S

IGF1 mouse monoclonal antibody, clone AT6F8, Purified


USD 230.00

2 Weeks*

Size
    • 50 ul

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Specifications

Product Data
Clone Name AT6F8
Applications ELISA, IF, WB
Recommended Dilution The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1/1000.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Recombinant human IGF1 (49-118aa) purified from E. coli.
Specificity Recognizes Human IGF1. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens insulin like growth factor 1 (IGF1), transcript variant 4
Background Insulin-like growth factor 1(IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene. IGF-1 has also been referred to as a Sulfation factor and its effects were termed nonsuppressible insulin-like activity (NSILA) in the 1970s. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin, is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7,649 daltons.
Synonyms IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.