DUSP3 Mouse Monoclonal Antibody [Clone ID: AT9E6]

CAT#: AM50634PU-S

DUSP3 mouse monoclonal antibody, clone AT9E6, Purified

Product Images

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human DUSP3 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: HeLa cell lysate Lane 2.: HepG2 cell lysate Lane 3.: Jurkat cell lysate Lane 4.: MCF7 cell lysate Lane 5.: 293T cell lysate Lane 6.: U87MG cell lysate Lane 7.: K562 cell lysate

Specifications

Product Data

• Clone Name: AT9E6
• Applications: ELISA, WB
• Recommended Dilution: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution for Western blot analysis is 1:3000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant human DUSP3 (1-185aa) purified from E. coli.
• Formulation: Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Protein-A affinity chromatography
• Gene Name: Homo sapiens dual specificity phosphatase 3 (DUSP3)
• Database Link:
  Entrez Gene 1845 Human
• Background: DUSP3, also known as Dual specificity protein phosphatase 3, is ictivate their target kises by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kise superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kises, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
• Synonyms: VHR

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway