Alpha-actinin-1 / ACTN1 Mouse Monoclonal Antibody [Clone ID: AT1D10]

CAT#: AM50637PU-N

Alpha-actinin-1 / ACTN1 mouse monoclonal antibody, clone AT1D10, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name AT1D10
Applications ELISA, FC, IF, WB
Recommended Dilution ELISA.
Western blot.

Flow cytometry.
Immunofluorescence.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human ACTN1 (1-249aa) purified from E. coli.
Formulation Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
State: Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Protein-A affinity chromatography
Gene Name Homo sapiens actinin alpha 1 (ACTN1), transcript variant 1
Background ACTN1 also known as Actinin, alpha 1. ACTN1 functions as an actin-binding-protein. ACTN1 determines the motility of keratinocytes by regulating the organization of the actin cytoskeleton, focal adhesion, and hemidesmosome proteins complexes, thereby modulating cell speed, lamellipodial dymics, and directed migration.
Synonyms Alpha actinin cytoskeletal isoform, Non-muscle alpha-actinin 1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Systemic lupus erythematosus, Tight junction

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.