Ncr1 Rat Monoclonal Antibody [Clone ID: 29A1.4]

CAT#: AM60015LE-N

Ncr1 rat monoclonal antibody, clone 29A1.4, Low Endotoxin

Specifications

Product Data

• Clone Name: 29A1.4
• Applications: FC, FN
• Recommended Dilution: Flow cytometry: 1/10-1/20, use 10µl of this suggested working dilution to label 10e6 cells in 100µl.
  Functional assays.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: NKP46-IgG1 Fc fusion protein
• Specificity: This antibody (clone 29A1.4) recognizes natural killer cell p46 related protein (NKp46) also known as CD335. Staining is not strain specific and the antibody has been used to stain C57BL/6, SJL, CBA/CA and BALB/c mouse strains. Clone 29A1.4 also activates NK cells in vitro. It does not deplete NK cells in vivo.
• Formulation: PBS
  State: Low Endotoxin
  State: Liquid purified IgG
  Preservative: None
• Concentration: 1.0 mg/ml
• Database Link:
  Entrez Gene 17086 Mouse
• Background: CD335 is uniquely expressed by resting and activated natural killer (NK) cells, but no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. It is a major NK cell lysis receptor for autologous pathogen-infected and tumor target cells during natural cytotoxicity responses. Ligands of CD335 include viral hemagglutinins (HAs) and heparan sulfate proteoglycans (HSPGs) on the surface of tumor cells.
• Synonyms: NCR1, LY94, NKp46