Ncr1 Rat Monoclonal Antibody [Clone ID: 29A1.4]

CAT#: AM60015PU-S

Ncr1 rat monoclonal antibody, clone 29A1.4, Purified

Specifications

Product Data

• Clone Name: 29A1.4
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/10-1/20 diluted antibody to label 10⁶ cells in 100 µl.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: NKP46-IgG1 Fc fusion protein
• Specificity: This antibody (clone 29A1.4) recognizes natural killer cell p46 related protein (NKp46) also known as CD335. Staining is not strain specific and the antibody has been used to stain C57BL/6, SJL, CBA/CA and BALB/c mouse strains.
  Clone 29A1.4 also activates NK cells in vitro. It does not deplete NK cells in vivo.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Database Link:
  Entrez Gene 17086 Mouse
• Background: CD335 is uniquely expressed by resting and activated natural killer (NK) cells, but no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. It is a major NK cell lysis receptor for autologous pathogen-infected and tumor target cells during natural cytotoxicity responses. Ligands of CD335 include viral hemagglutinins (HAs) and heparan sulfate proteoglycans (HSPGs) on the surface of tumor cells.
• Synonyms: NCR1, LY94, NKp46