BMX Rabbit Polyclonal Antibody

CAT#: AP00146PU-N

BMX rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 0.5-4 μg/ml; Jurkat cell lysate can be used as a positive control.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 43 of human Etk
• Specificity: The antibody recognizes 76 kDa Etk.
• Formulation: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
  State: Aff - Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Immunoaffinity purified
• Storage: Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens BMX non-receptor tyrosine kinase (BMX), transcript variant 2
• Database Link:
  Entrez Gene 12169 MouseEntrez Gene 367786 RatEntrez Gene 660 Human
• Background: Etk is a member of the Bruton's tyrosine kinase family. Etk is expressed in a variety of hematopoietic, epithelial and endothelial cells. It participates in multiple signal transduction pathways. Phosphorylation of tyrosine 566 by Src kinase is required for activation of Etk in vivo. In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at tyrosine 40.
• Synonyms: NTK38, ETK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase