WNT2 Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot: 0.5-4 μg/ml. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide surrounding amino acid 45 of Human Wnt-2 |
Specificity | The antibody recognizes 34 kDa Wnt-2 in Human, Mouse samples and to a lesser extent Rat. |
Formulation | PBS containing 30% Glycerol, 0.5% BSA and 0.01% Thimerosal State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | 0.2 mg/ml |
Purification | Affinity Chromatography |
Database Link | |
Background | Wnt family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 functions as a key regulator of cellular adhesion. Wnt-3 is also involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-1, Wnt-3 and Wnt-10b have been implicated along with FGF-3 in the development of mouse mammary tumor virus induced mouse mammary carcinomas. |
Synonyms | Protein Wnt-2, INT1L1, IRP, Int-1-like protein 1, Int-1-related protein |
Note | Blocking peptide Cat.-No AP00246CP-N is available separately. |
Reference Data |
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