SGLT1 (SLC5A1) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | Western Blot: 0.5-4 µg/ml. Jurkat cell lysate can be used as a Positive Control. Immunohistochemistry: 5 µg/ml. |
| Reactivities | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide surrounding amino acid 594 of Human SGLT-1 |
| Specificity | The antibody detects 73 kDa SGLT-1 from Human samples and in a lesser extent Mouse and Rat. A ~50 kDa cleavage fragment can also be detected in Jurkat cell lysate. |
| Formulation | PBS, pH 7.2 containing 30% Glycerol State: Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.01% Thimerosal |
| Concentration | 0.5 mg/ml |
| Purification | Affinity Chromatography on Protein A |
| Database Link | |
| Background | Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally related substances across cellular membranes. Two families of glucose transporter have been identified: the facilitated diffusion glucose transporter family (GLUT family), also known as uniporters and the sodium dependent glucose transporter family (SGLT family) also known as cotransporters or symporters. The SGLT1 gene encodes a protein that is involved in the active transport of glucose and galactose into eukaryotic and some prokaryotic cells. |
| Synonyms | Sodium/glucose cotransporter 1, NAGT |
| Note | Blocking Peptide (Cat.-No AP00343CP-N) is available separately. |
| Reference Data | |
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