Collagen V (COL5A1) Goat Polyclonal Antibody

CAT#: AP00360PU-N

Collagen V (COL5A1) goat polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunoblotting.
  Immunofluorescence.
  Immunohistochemistry on frozen sections.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Human type V collagen
• Specificity: This antibody reacts to Collagen V. This antibody shows less than 10% reactivity with collagen type I, II, III, IV, and VI. It may react with collagen V from other species. Reactivity with other ECM proteins has not been tested.
• Formulation: Borate buffered saline
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens collagen type V alpha 1 (COL5A1), transcript variant 1
• Database Link:
  Entrez Gene 1289 Human
• Background: Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.
• Synonyms: COL5A1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion