PDE5A Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | IHC, IP, WB |
Recommended Dilution | Western blot. Immunohistochemistry. Immunoprecipitation. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Designed from the C-terminal region common to the 5A isoform. |
Specificity | The antibody selectively detects proteins corresponding to the PDE5A. |
Formulation | State: Serum State: Liquid diluted serum |
Database Link | |
Background | Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE5 enzyme belongs to a family of cGMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cGMP. |
Synonyms | PDE5, cGMP-specific 3',5'-cyclic phosphodiesterase, EC=3.1.4.35, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE |
Reference Data |
Documents
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