PDE5A Rabbit Polyclonal Antibody

CAT#: AP00658SU-N

PDE5A rabbit polyclonal antibody, Serum

Product Images

Western blot using AP00658SU-N (1/2,000) against lysate from COS cells transfected with the indicated human PDE isoform.

Specifications

Product Data

• Applications: IHC, IP, WB
• Recommended Dilution: Western blot.
  Immunohistochemistry.
  Immunoprecipitation.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Designed from the C-terminal region common to the 5A isoform.
• Specificity: The antibody selectively detects proteins corresponding to the PDE5A.
• Formulation: State: Serum
  State: Liquid diluted serum
• Database Link:
  Entrez Gene 8654 Human
• Background: Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE5 enzyme belongs to a family of cGMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cGMP.
• Synonyms: PDE5, cGMP-specific 3',5'-cyclic phosphodiesterase, EC=3.1.4.35, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE