Renin (REN) Sheep Polyclonal Antibody

CAT#: AP00945PU-N

Renin (REN) sheep polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/50000.
  Western blot: 1/5,000.
  Immunohistochemistry: 1/1,000.
• Reactivities: Mouse, Rat
• Host: Sheep
• Clonality: Polyclonal
• Immunogen: Recombinant Rat Prorenin
• Specificity: This antibody reacts with Rat and Mouse Renin.
  Other species not tested.
• Formulation: 0.05M Sodium Phosphate, 0.1M Sodium Chloride, 1mM EDTA, pH 6.6
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: None
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Upon receipt, store (in aliquots) at -20°C to -80°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Renin also occurs in other organs than the kidney, e.g., in the brain, where it is implicated in the regulation of numerous activities.
• Synonyms: REN, Angiotensinogenase, angiotensin-forming enzyme, HNFJ2