SSBP1 Rabbit Polyclonal Antibody

CAT#: AP01371PU-N

SSBP1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of SSBP1 antibody (Cat.-No.: AP01371PU-N) in extracts from HUVEC.

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  Immunohistochemistry (IHC) analyzes of SSBP1 antibody (Cat.-No.: AP01371PU-N) in paraffin-embedded human pancreas tissue

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immuofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of SSBP1 protein.
• Formulation: Phosphate buffered saline (PBS), pH~7.2 with 0.05% Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~17 kDa
• Gene Name: Homo sapiens single stranded DNA binding protein 1 (SSBP1), transcript variant 5
• Database Link:
  Entrez Gene 54304 RatEntrez Gene 381760 MouseEntrez Gene 6742 Human
• Background: The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Mitochondrial single-stranded DNA-binding protein (mtSSB or SSBP1) is necessary for mtDNA replication. SSBP1 is a homotetramer that binds preferentially and cooperatively to single-stranded DNA. It is localized to the mitochondria in normal and neoplastic human tissue of different origin, function, and differentiation, and is likely involved in mitochondrial DNA replication.
• Synonyms: SSBP, Mt-SSB, mtSSB

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: DNA replication, Homologous recombination, Mismatch repair