FGF22 Rabbit Polyclonal Antibody

CAT#: AP01375PU-N

FGF22 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of FGF-22 antibody (Cat.-No.: AP01375PU-N) in extracts from Jurkat cells.

• 

  Immunohistochemistry (IHC) analyzes of FGF-22 antibody (Cat.-No.: AP01375PU-N) in paraffin-embedded human ovary tissue

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: FGF-22 antibody detects endogenous levels of FGF-22 protein. (region surrounding Ala96)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Predicted Protein Size: ~ 20 kDa
• Gene Name: Homo sapiens fibroblast growth factor 22 (FGF22), transcript variant 1
• Database Link:
  Entrez Gene 67112 MouseEntrez Gene 170579 RatEntrez Gene 27006 Human
• Background: Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. Fibroblast growth factor-22 (FGF-22) is a secreted protein whose gene is localized to human chromosome 19p13.3. FGF-22 is expressed preferentially in the inner root sheath of the hair follicle, suggesting that it is important in hair development.
• Synonyms: Fibroblast growth factor 22, FGF-22

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton