ERAS Rabbit Polyclonal Antibody

CAT#: AP01406PU-N

ERAS rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of E-Ras antibody (Cat.-No.: AP01406PU-N) in extracts from Jurkat cells.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: E-Ras antibody detects endogenous levels of E-Ras protein. (region surrounding Cys226)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 25 kDa
• Gene Name: Homo sapiens ES cell expressed Ras (ERAS)
• Database Link:
  Entrez Gene 3266 Human
• Background: ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.
• Synonyms: GTPase ERas, E-Ras, HRASP

Reference Data

• Protein Families: Druggable Genome