JUNB pSer79 Rabbit Polyclonal Antibody

CAT#: AP02327PU-N

JUNB pSer79 rabbit polyclonal antibody, Aff - Purified

Product Images

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JunB (phospho-Ser79) antibody.

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  Figure 2: Immunofluorescence staining of methanol-fixed HeLa cells using JunB (pSer79) Antibody

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunofluorescence: 1/100-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide derived from Human JunB around the phosphorylation site of Serine 79 (G-A-SP-L-K).
• Specificity: This antibody detects endogenous levels of JunB only when phosphorylated at Serine 79.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 43 kDa
• Database Link:
  Entrez Gene 3726 Human
• Background: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge.
  JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
• Synonyms: JUNB