Myosin Light Chain 2 (MYL2) Rabbit Polyclonal Antibody
Other products for "MYL2"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around amino acids 17~21 (A-T-S-N-V) derived from Human Myosin Light Chain 2 Protein. |
Specificity | This antibody AP02680PU detects endogenous levels of total Myosin Light Chain 2 protein. |
Formulation | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography using epitope-specific immunogen. |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 18 kDa (SDS-PAGE) |
Gene Name | Homo sapiens myosin light chain 2 (MYL2) |
Database Link | |
Background | Myosin light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. |
Synonyms | MLC-2v, MLC-2 |
Reference Data | |
Protein Pathways | Cardiac muscle contraction, Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Tight junction |
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