MTGR1 (CBFA2T2) Sheep Polyclonal Antibody

CAT#: AP05066PU-N

MTGR1 (CBFA2T2) sheep polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1 - 10 µg/ml.
• Reactivities: Human
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: C terminal portion of recombinant protein
• Specificity: This antibody reacts to Myeloid Tumor Related Gene (MTGR1) (AML1-MTG8 binding protein or ETH).
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Purified
  State: Liquid purified Ig (0.2µm sterile filtered)
• Concentration: Lot specific
• Gene Name: Homo sapiens core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (CBFA2T2), transcript variant 3
• Database Link:
  Entrez Gene 9139 Human
• Background: Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF-dependent proliferation of L-G cells and to interfere with AML1-dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
• Synonyms: EHT, MTGR1, MTG8-like protein, MTG8-related protein 1

Reference Data

• Protein Families: Transcription Factors