G protein alpha inhibitor 1 (GNAI1) (+ GNAI2) Rabbit Polyclonal Antibody

CAT#: AP05163PU-N

G protein alpha inhibitor 1 (GNAI1) (+ GNAI2) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 5 - 10 µg/ml.
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide corresponding to amino acids 345 - 354 of Gialpha1 and 346-355 of Gialpha2.
• Specificity: This antibody reacts to Gi alpha 1/2.
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: Lot specific
• Gene Name: Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1), transcript variant 1
• Database Link:
  Entrez Gene 14677 MouseEntrez Gene 25686 RatEntrez Gene 2770 Human
• Background: GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of alpha-subunits (alphai1, aalphai2 and alphai3)
• Synonyms: GNAI1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction