OGR1 (GPR68) Rabbit Polyclonal Antibody

CAT#: AP05165PU-N

OGR1 (GPR68) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis using OGR1 antibody on cells transfected with OGR1 protein at 10 ug/ml. Blot developed using Pierce's SuperSignal West Femto Maximum Sensitvity Substrate.

Specifications

Product Data

• Applications: FN, IHC, WB
• Recommended Dilution: Western Blot: 5-10 µg/ml.
  Western blot should be visualized using a high sensitivity secondary/substrate system.
  Neutralization.
  Immunohistochemistry.
  Positive Control: OGR1 transfected cell lysate.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein derived from Human OGR1 (GPR68) protein
• Specificity: This antibody recognizes OGR1.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.08% Sodium Azide
• Concentration: Lot specific
• Purification: Ammonium Sulfate Precipitation
• Database Link:
  Entrez Gene 8111 Human
• Background: OGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing. SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.
• Synonyms: Sphingosylphosphorylcholine receptor, G-protein coupled receptor 68, GPR12A