UGT8 Rabbit Polyclonal Antibody

CAT#: AP05205PU-N

UGT8 rabbit polyclonal antibody, Purified

Product Images

Western blot analysis using Ceramide Glycosyltransferase antibody on 7 ug of rat kidney lysate. Antibody used at 1 ug/ml. Visualized using Pierce West Femto substrate system. Secondary used at 1:75k dilution. Exposure for 60 seconds.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: 5-10 µg/ml.
  Positive Control: Found in all tissues examined.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from Human Ceramide Glycosyltransferase Protein
• Specificity: This antibody recognizes Human Ceramide Glycosyltransferase. Other species not tested.
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.08% Sodium Azide
• Concentration: Lot specific
• Purification: Ammonium Sulfate Precipitation
• Gene Name: Homo sapiens UDP glycosyltransferase 8 (UGT8), transcript variant 1
• Database Link:
  Entrez Gene 7368 Human
• Background: May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
• Synonyms: UDP-galactose-ceramide galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism