UGT8 Rabbit Polyclonal Antibody
Other products for "UGT8"
Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA. Western Blot: 5-10 µg/ml. Positive Control: Found in all tissues examined. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from Human Ceramide Glycosyltransferase Protein |
Specificity | This antibody recognizes Human Ceramide Glycosyltransferase. Other species not tested. |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.08% Sodium Azide |
Concentration | Lot specific |
Purification | Ammonium Sulfate Precipitation |
Gene Name | Homo sapiens UDP glycosyltransferase 8 (UGT8), transcript variant 1 |
Database Link | |
Background | May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates. |
Synonyms | UDP-galactose-ceramide galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
Documents
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