SAMD8 Rabbit Polyclonal Antibody

CAT#: AP05209PU-N

SAMD8 rabbit polyclonal antibody, Purified

Product Images

Western blot analysis using Sphingomyelin Synthase r on recombinant protein (Lane A) antibody alone. Anti Rabbit secondary used at 1/25K Exposure for 30 seconds.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: 5-10 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Full-length recombinant sphingomyelin synthase r fusion protein.
• Specificity: This antibody reacts to Sphingomyelin synthase-related protein 1.
• Formulation: Phosphate buffered saline with 0.08% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: Lot specific
• Gene Name: Homo sapiens sterile alpha motif domain containing 8 (SAMD8), transcript variant 2
• Database Link:
  Entrez Gene 142891 Human
• Background: Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.
• Synonyms: FLJ25082; SMSr

Reference Data

• Protein Families: Transmembrane