NSMAF Rabbit Polyclonal Antibody

CAT#: AP05299PU-N

NSMAF rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot (1:400 starting dilution).
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from human NSMAF protein
• Specificity: This antibody detects N-SMase Activation Associated Factor.
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: Lot specific
• Purification: Affinity chromatography
• Gene Name: Homo sapiens neutral sphingomyelinase activation associated factor (NSMAF), transcript variant 1
• Database Link:
  Entrez Gene 8439 Human
• Background: Novel adaptor protein which mediates the activation of sphingomyelinase by receptors such as tumor necrosis factor receptor type 1 and CD40 and subsequent apoptosis in cardiomyocytes. Inhibition of this factor may provide a novel intervention point for reducing ischemia/reperfusion injury.
• Synonyms: FAN, N-SMase activation Factor

Reference Data

• Protein Families: Druggable Genome