Luteinizing Hormone beta (LHB) Sheep Polyclonal Antibody

CAT#: AP05458PU-N

Luteinizing Hormone beta (LHB) sheep polyclonal antibody, Purified

Specifications

Product Data

• Recommended Dilution: IRMA.
  Radioimmunoassays: >1/50,000 initial dilution in 125I RIA overnight assay.
  ELISA: Has been used for coating and also as a capture antibody in a two site assay in conjunction with other monoclonal antibodies.
• Reactivities: Human
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Highly purified human pituitary luteinizing hormone.
• Specificity: This antibody recognises human luteinizing hormone, a gonadotrophic hormone found in the anterior lobe of the pituitary gland.
  TSH: 20%
  hCG: 6%
  FSH: 6%
  Prolactin: 0.1%
  hPL: 0.1%
• Formulation: Phosphate buffered saline, pH 7.2 containing 0.09% Sodium Azide (NaN3)
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens luteinizing hormone beta polypeptide (LHB)
• Database Link:
  Entrez Gene 3972 Human
• Background: Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
• Synonyms: LH

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: GnRH signaling pathway, Neuroactive ligand-receptor interaction