Ppard (N-term) Rabbit Polyclonal Antibody

CAT#: AP05660PU-N

Ppard (N-term) rabbit polyclonal antibody, Purified


USD 425.00

5 Days*

Size
    • 50 ug

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Specifications

Product Data
Applications ELISA, WB
Recommended Dilution ELISA: 1:2000 - 1:8000.
Western Blot: 1:500 - 1:2000; detects a band of approximately 55kDa in heart whole cell lysates.
Reactivities Human, Monkey, Mouse, Rabbit, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.
Specificity This antibody detects peroxisome proliferator-activated receptor, delta (PPARD).
Formulation Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3)
State: Purified
State: Liquid purified IgG
Concentration 1.0mg/ml
Gene Name Mus musculus peroxisome proliferator activator receptor delta (Ppard)
Background PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta.
PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.
Synonyms PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.