CX3CR1 (N-term) Rabbit Polyclonal Antibody
Other products for "CX3CR1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Western Blot: 0.5-1.0 µg/ml. Detects a band of approximately 50kDa in Human spleen cell lysates. Immunohistochemistry on Paraffin Sections: 2.0 µg/ml. Requires Antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Positive Control: Human Heart Tissue. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A peptide corresponding to amino acids 2-21 of Human CX3CR1. |
Specificity | This antibody recognizes an epiptope within the N-terminal region (NT) of Human CX3CR1, a 40.4kDa seven trans-membrane protein. |
Formulation | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.02% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens C-X3-C motif chemokine receptor 1 (CX3CR1), transcript variant 4 |
Database Link | |
Background | CX3CR1, known also as fractalkine receptor, is the receptor for CX3CL1 and acts as a co-receptor with CD4 for the HIV-1 envelope protein. It is expressed in a variety of human tissues and mediates leucocyte adhesion and migration. |
Synonyms | CX3C chemokine receptor 1, C-X3-C CKR-1,CMKBRL1, CMK-BRL-1 |
Reference Data | |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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