Dnm1 pSer774 Sheep Polyclonal Antibody

CAT#: AP05892PU-N

Dnm1 pSer774 sheep polyclonal antibody, Purified


USD 610.00

5 Days*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Immunofluorescence.
Immunohistochemistry on Frozen Sections.
Western Blot (1/1000): This antibody detects a band of approximately 95kDa in Rat hippocampus lysates.
For the detection of Phosphoproteins, Serine Phosphatase inhibitors such as 10mM Sodium Fluoride should be added to the sample buffer. Milk or other casein-based blocking solutions are not recommended as casein is a Phosphoprotein and its use can result in high background.
Reactivities Bovine, Canine, Chicken, Human, Monkey, Mouse, Rat
Host Sheep
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic phosphopeptide corresponding to an amino acid sequence within Dynamin which includes phosphorylated Ser774.
Specificity This antibody is specific for Dynamin when phosphorylated at Serine 774.
Formulation 10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% BSA and 50% Glycerol.
State: Purified
State: Liquid purified IgG fraction.
Purification Affinity Chromatography.
Background Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.
Synonyms DNM1, DNM
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.