Protein Kinase D2 (PRKD2) Rabbit Polyclonal Antibody

CAT#: AP06570PU-N

Protein Kinase D2 (PRKD2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PKD2 Antibody in extracts from NIH/3T3 cells treated with PMA 250ng/ml 15'.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 840-890 of Human PKD2.
• Specificity: This antibody detects endogenous levels of PKD2 protein.
  (region surrounding Ala872)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Predicted Protein Size: ~96 kDa
• Gene Name: Homo sapiens protein kinase D2 (PRKD2), transcript variant 2
• Database Link:
  Entrez Gene 101540 MouseEntrez Gene 292658 RatEntrez Gene 25865 Human
• Background: The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: PKC-D2, nPKC-D2, HSPC187

Reference Data

• Protein Families: Druggable Genome, Protein Kinase