DLX3 Rabbit Polyclonal Antibody

CAT#: AP06641PU-N

DLX3 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Dlx-3 antibody in extracts from 293 cells.

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  Immunohistochemistry (IHC) analyzes of Dlx-3 antibody in paraffin-embedded human heart tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 71-120 of Human Dlx-3.
• Specificity: This antibody detects endogenous levels of Dlx-3 protein.
  (region surrounding Asp107)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
• Predicted Protein Size: ~ 45 kDa
• Gene Name: Homo sapiens distal-less homeobox 3 (DLX3)
• Database Link:
  Entrez Gene 13393 MouseEntrez Gene 1747 Human
• Background: Dlx genes are a highly conserved family of six different (Dlx1–6) homeo boxcontaining genes that share homology with distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. Dlx genes are expressed in spatially and temporally restricted patterns in craniofacial primordia, basal telencephalon and diencephalon, and in distal regions of extending appendages, including the limb and the genital bud. The differential expression of Dlx influences patterning, morphogenesis and histogenesis in these tissues. The Dlx gene products can activate transcription and are localized primarily to the nucleus, although Dlx-5 can be found in the cytoplasm. Dlx proteins influence different stages of proper tissue development, including patterning of the orofacial skeleton (craniofacial ectomesenchyme) and differentiation of structures within and between teeth.
• Synonyms: DLX-3, Homeobox protein DLX3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors