Cleavage stimulation factor 2 (CSTF2) Rabbit Polyclonal Antibody

CAT#: AP06681PU-N

Cleavage stimulation factor 2 (CSTF2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of CstF-64 antibody in extracts from 293 cells.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids N-terminus of Human CstF-64.
• Specificity: This antibody detects endogenous levels of CstF-64 protein.
  (region surrounding Arg46)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 64 kDa
• Gene Name: Homo sapiens cleavage stimulation factor, 3' pre-RNA, subunit 2 (CSTF2), transcript variant 2
• Database Link:
  Entrez Gene 108062 MouseEntrez Gene 1478 Human
  UniProt ID P33240
• Background: The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific. In the developing nervous system AKT is a critical mediator of growth factor induced neuronal survival. Survival factors can suppress apoptosis in a transcription independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene (referenced from entrez gene).
• Synonyms: CSTF 64 kDa subunit, CstF-64, CSTF64, CF-1 64 kDa subunit