Cytokeratin 19 (KRT19) (21-40) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Applications | ELISA, IHC |
| Recommended Dilution | ELISA: 1/1000. Immunohistochemistry on Paraffin Sections: 5 µg/ml. |
| Reactivities | Human, Monkey, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide comprised of amino acids 21-40 of Mouse Cytokeratin-19 |
| Specificity | This antibody detects Keratin, Type I Cytoskeletal 19 (KRT19) at aa 21-40. |
| Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (w/v) Sodium Azide |
| Concentration | lot specific |
| Purification | Protein G Chromatograpgy |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Database Link | |
| Background | Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. KRT19 is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. |
| Synonyms | Cytokeratin-19, Keratin-19, KRT19, CK19, K19 |
| Reference Data | |
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