TLR10 Rabbit Polyclonal Antibody

CAT#: AP07366PU-N

TLR10 rabbit polyclonal antibody, Purified

Product Images

Figure 1. TLR10 antibody staining of Formalin-Fixed Paraffin-Embedded Brain Cerebellum.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 0.5 - 1 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide -KLH conjugated corresponding to 14 amino acids near the middle of TLR10.
• Specificity: This antibody recognizes CD290/TLR10.
• Formulation: Phosphate buffered saline containing 0.02% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: 1 mg/ml
• Purification: Ion Exchange Chromatography.
• Database Link:
  Entrez Gene 81793 Human
• Background: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is highly homologous to TLRs 1 and 6 and is most highly expressed in lymphoid tissues. Most recently genetic variation in TLR10 has been associated with contributing to asthma risk. It should be noted that TLR10 exists in mice only as a pseudogene.
• Synonyms: Toll-like receptor 10, UNQ315/PRO358