PD1 (PDCD1) Rabbit Polyclonal Antibody

CAT#: AP07723PU-N

PD1 (PDCD1) rabbit polyclonal antibody, Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

Product Images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Immunohistochemistry on FFPE-Sections: ~2.5 - 5 µg/ml (after heat induced antigen retrieval in pH 6.0 citrate buffer).
Immunofluorescence.
Western Blot. Expect a band at ~ 47 kD in size.
THP-1 cell lysate can be used as positive control.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to 16 Amino Acid from near the carboxy terminus of Human PDCD1.
Specificity This antibody is specific to CD279/PDCD1
Formulation PBS containing 0.02% Sodium Azide as preservative.
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Store the antibody undiluted at 2-8°C for up to 3 months or at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name programmed cell death 1
Background This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Synonyms Protein PD-1, hPD-1, PDCD1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.