MMP27 (445-459) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Applications | ELISA, IHC |
| Recommended Dilution | ELISA: 1/1000. Immunohistochemistry on Paraffin Sections: 10 µg/ml. |
| Reactivities | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic Peptide corresponding to Amino acids 445 to 459 of Human MMP27 |
| Specificity | This antibody recognises Matrix Metalloproteinase 27 (MMP27) at aa 445-459. |
| Formulation | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
| Concentration | 1 mg/ml |
| Purification | Protein G Chromatography |
| Database Link | |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The recently discovered 513 amino acid human MMP27 protein is located primarily in extracellular spaces in the extracellular matrix, and maps to chromosome 11q24. To date there are very few publications on MMP27, and very little information about sources or size for the protein. |
| Synonyms | Matrix metalloproteinase-27, MMP27, UNQ2503/PRO5992 |
| Reference Data | |
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