Hepatitis B Core Antigen / HBcAg Rabbit Polyclonal Antibody

CAT#: AP08118PU-N

Hepatitis B Core Antigen / HBcAg rabbit polyclonal antibody, Ig Fraction

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry for Formalin-Fixed Paraffin Embedded (FFPE) Tissue Sections and Frozen Sections: Dilute 1/200-1/400 using polymer or streptavidin ~biotin system for 30 mins at room temperature.
  Positive control: Human liver infected with hepatitis B virus.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified hepatitis B core antigen.
• Specificity: Antibody to hepatitis B core antigen (anti-HBc) is considered a sensitive and specific serum marker of hepatitis B virus(HBV) infection.
  Cellular localization: Hepatocyte nuclei.
• Formulation: 10 mM PO4, 150 mM NaCl, pH 7.4 containing 0.05% Sodium Azide as preservative.
  State: Ig Fraction
  State: Total Ig fraction.
• Concentration: 3.5 mg/ml
• Purification: Protein A
• Background: Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection.
  The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
• Synonyms: HBV Capsid protein, HBV Core protein, p21.5