CCKBR (251-266) Goat Polyclonal Antibody
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 0.1 - 0.3 µg/ml. |
Reactivities | Human |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from an internal region of Human CCKBR |
Specificity | Recognizes Human Cholecystokinin B Receptor (CCKBR) at 251-266. |
Formulation | Tris Saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography |
Storage | Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers. |
Synonyms | CCKB Receptor, Cholecystokinin type B receptor, CCK-BR, CCKBR, CCKRB, Cholecystokinin-2 receptor, CCK2-R |
Reference Data |
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