P4HB Rabbit Polyclonal Antibody

CAT#: AP08767PU-N

P4HB rabbit polyclonal antibody, Aff - Purified

Product Images

AP08767PU-N P4HB antibody staining of Formalin-Fixed, Paraffin-Embedded Human small intestine at 1/50 dilution.

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  AP08767PU-N P4HB antibody staining of Formalin-Fixed, Paraffin-Embedded Human small intestine.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunocytochemistry: 1/50.
  Immunofluorescence: 1/50.
  Immunohistochemistry on Paraffin Sections: 1/50.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide conjugated to KLH derived from the sequence around Proline 329 of Human P4HB.
• Specificity: Recognizes endogenous levels of total P4HB.
• Formulation: 10mM Sodium HEPES, pH 7.5, 150mM Sodium Chloride, 0.1 mg/ml BSA, 50% Glycerol
  State: Aff - Purified
  State: Liquid purified IgG fraction
• Purification: Immunoaffinity Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 5034 Human
• Background: P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.
• Synonyms: Protein disulfide-isomerase, Protein Disulfide Isomerase, PDIA1, PO4DB, p55, P4HB, ERBA2L, Prolyl 4-hydroxylase subunit beta, ER marker, PDI
• Note: Predicted Molecular Weight: 57 kDa.