PCB (PC) (886-899) Goat Polyclonal Antibody

CAT#: AP08821PU-N

PCB (PC) (886-899) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

Product Images

Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution ELISA: 1/16000.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 0.03 - 0.1 µg/ml.
Reactivities Bat, Bovine, Canine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide from an Internal region of Human PC
Specificity Recognizes Pyruvate Carboxylase (PC) at aa 886-899.
Formulation Tris saline buffer, pH 7.3
State: Aff - Purified
State: Liquid purified Ig fraction
Stabilizer: 0.5% BSA
Preservative: 0.02% Sodium Azide
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name pyruvate carboxylase
Background Pyruvate Carboxylase (PC, PCB) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Synonyms Pyruvate carboxylase mitochondrial, PCB
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.