CCR6 (18-46) Goat Polyclonal Antibody

CAT#: AP08829PU-N

CCR6 (18-46) goat polyclonal antibody, Aff - Purified

Product Images

staining CCR6 at 5 ug/ml in paraffin-embedded Human Tonsil by Immunohistochemistry.

Specifications

Product Data

• Applications: ELISA, FC, IF, IHC
• Recommended Dilution: ELISA: 1/75000.
  Flow Cytometry: 1 - 3 µg/10E6 cells.
  Immunocytochemistry: 1/300.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to amino acids 18-46 of Human CD196/CCR6
• Specificity: This antibpdy recognizes Human CD196/CCR6 at aa 18-46.
• Formulation: PBS containing 1 mg/ml BSA as stabilizer and 0.09% Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 1235 Human
• Background: CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP 3 alpha). This receptor has been shown to be important for B lineage maturation and antigen driven B cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses.
  CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.
• Synonyms: C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, GPR29, STRL22, DRY6, GPR-CY4