PTP4A3 Rabbit Polyclonal Antibody

CAT#: AP09464PU-S

PTP4A3 rabbit polyclonal antibody, Aff - Purified


USD 230.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western blot: 1/500~1/1000.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PRL-3 around the site of 160.
Specificity Antibody AP09464PU detects transfected PRL-3 protein.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration 1.0 mg/ml
Purification Immunoaffinity Chromatography using epitope-specific immunogen.
Gene Name Homo sapiens protein tyrosine phosphatase type IVA, member 3 (PTP4A3), transcript variant 2
Background PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. It is consistently overexpressed in colon cancer metastasis.
Synonyms PRL-3, PRL-R
Reference Data
Protein Families Druggable Genome, Phosphatase

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.