MARCKS pSer170 Rabbit Polyclonal Antibody

CAT#: AP09469PU-N

MARCKS pSer170 rabbit polyclonal antibody, Aff - Purified


USD 300.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western blot: 1/500~1/1000.
Immunohistochemistry on Paraffin Sections: 1/50~1/100.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MARCKS around the phosphorylation site of Serine 170 (G-F-Sp-F-K).
Specificity This antibody detects endogenous levels of MARCKS only when phosphorylated at Threonine 170.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Gene Name Homo sapiens myristoylated alanine rich protein kinase C substrate (MARCKS)
Background MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.
Synonyms Myristoylated alanine-rich C-kinase substrate, MACS, PRKCSL
Reference Data
Protein Families Druggable Genome
Protein Pathways Fc gamma R-mediated phagocytosis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.