c Rel (REL) Rabbit Polyclonal Antibody

CAT#: AP09497PU-S

c Rel (REL) rabbit polyclonal antibody, Aff - Purified

Product Images

Immunofluorescence staining of methanol-fixed HeLa cells using Rel Antibody

Specifications

Product Data

• Applications: IF
• Recommended Dilution: Immunofluorescence: 1/100 - 1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthesized non-phosphopeptide derived from human Rel around the phosphorylation site of serine 503 (T-S-SP-D-S)
• Specificity: Rel Antibody detects endogenous levels of total Rel protein.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
  State: Aff - Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog (REL), transcript variant 1
• Database Link:
  Entrez Gene 5966 Human
• Background: c-Rel is the cellular cognate of v-Rel, the avian reticuloendo-theliosis virus strain T transforming gene. V-Rel encodes a 59kDa phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non-transformed fibroblasts, in contrast to the c-Rel protein which is cytoplasmic. C-Rel was shown to represent a constituent of the kB site binding transcription factor NFkB, which plays a crucial role in the expression of immunoglobulin k light chain gene.
• Synonyms: c-Rel

Reference Data

• Protein Families: Druggable Genome, Transcription Factors